Don Alonso Leal y Tovar, Coronel Graduado de Infantería ... : bando

Bando fechado en Zamora, y Marzo 27 de 1824, firmado por Alonso Leal y TovarCopia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 2009-201

Rabifier2: an improved bioinformatic classifier of Rab GTPases

SUMMARY: The Rab family of small GTPases regulates and provides specificity to the endomembrane trafficking system; each Rab subfamily is associated with specific pathways. Thus, characterization of Rab repertoires provides functional information about organisms and evolution of the eukaryotic cell. Yet, the complex structure of the Rab family limits the application of existing methods for protein classification. Here, we present a major redesign of the Rabifier, a bioinformatic pipeline for detection and classification of Rab GTPases. It is more accurate, significantly faster than the original version and is now open source, both the code and the data, allowing for community participation. AVAILABILITY AND IMPLEMENTATION: Rabifier and RabDB are freely available through the web at http://rabdb.org. The Rabifier package can be downloaded from the Python Package Index at https://pypi.python.org/pypi/rabifier, the source code is available at Github https://github.com/evocell/rabifier

Quantum Key Distribution Over Quantum Repeaters with Encoding: Using Error Detection as an Effective Postselection Tool

We propose a postselection technique, based on quantum error detection, for quantum key distribution (QKD) systems that run over quantum repeaters with encoding. In such repeaters, quantum error-correction techniques are used for entanglement distillation. By developing an analytical approach to study such quantum repeaters, we show that, in the context of QKD, it is often more efficient to use the error-detection, rather than the error-correction, capability of the underlying code to sift out cases where an error has been detected. We implement our technique for three-qubit repetition codes by modeling different sources of error in crucial components of the system. We then investigate in detail the impact of such imperfections on the secret key generation rate of the QKD system, and how one can use the information obtained during entanglement swapping and decoding stages to maximize the rate. For benchmarking purposes, we specify the maximum allowed error rates in different components of the setup below which positive key rates can be obtained

Delimitation of Cybernetics meanings and other technologic word in Journalism

Se utilizan en tiempos actuales diversas acepciones para cuanto se refiere a la automatización de los procesos periodísticos y más desde la irrupción de la Red en su uso social con cada día una mayor aceptación en personas de todas las edades. Cuando nos referimos a la denominación a través de los términos, bien sea en España o en Latinoamericana, países donde convivimos con el mismo idioma, aplicamos diferentes palabras: Cibernética, Computación, Digitalización, Electrónica, Informática. Nos proponemos delimitar el vocablo más usado para un tratamiento periodístico y su campo lexicológico para precisar su aplicación y armonizar el quehacer profesional en sus formas.Nowadays we use different meanings concerning at the journalistic course automation, and increase since the Internet irruption in it social use, with more approval in all age persons each time. When we refer to the denomination through the terms, in Spain or in Latin America, countries where we cohabit with the same language, we apply different words: Computer Science, Cybernetics, Compute, Digitalization and Electronics. This investigation brings us nearer to the usual word delimitation for a journalistic treatment and lexicological field, to specify the application and to harmonize the professional duty and its conventions

Superpulsed low-level laser therapy protects skeletal muscle of mdx mice against damage, inflammation and morphological changes delaying dystrophy progression.

Aim: To evaluate the effects of preventive treatment with low-level laser therapy (LLLT) on progression of dystrophy in mdx mice. Methods: Ten animals were randomly divided into 2 experimental groups treated with superpulsed LLLT (904 nm, 15 mW, 700 Hz, 1 J) or placebo-LLLT at one point overlying the tibialis anterior muscle (bilaterally) 5 times per week for 14 weeks (from 6th to 20th week of age). Morphological changes, creatine kinase (CK) activity and mRNA gene expression were assessed in animals at 20th week of age. Results: Animals treated with LLLT showed very few morphological changes in skeletal muscle, with less atrophy and fibrosis than animals treated with placebo-LLLT. CK was significantly lower (p = 0.0203) in animals treated with LLLT (864.70 U.l−1, SEM 226.10) than placebo (1708.00 U.l−1, SEM 184.60). mRNA gene expression of inflammatory markers was significantly decreased by treatment with LLLT (p<0.05): TNF-α (placebo-control = 0.51 µg/µl [SEM 0.12], - LLLT = 0.048 µg/µl [SEM 0.01]), IL-1β (placebo-control = 2.292 µg/µl [SEM 0.74], - LLLT = 0.12 µg/µl [SEM 0.03]), IL-6 (placebo-control = 3.946 µg/µl [SEM 0.98], - LLLT = 0.854 µg/µl [SEM 0.33]), IL-10 (placebo-control = 1.116 µg/µl [SEM 0.22], - LLLT = 0.352 µg/µl [SEM 0.15]), and COX-2 (placebo-control = 4.984 µg/µl [SEM 1.18], LLLT = 1.470 µg/µl [SEM 0.73]). Conclusion: Irradiation of superpulsed LLLT on successive days five times per week for 14 weeks decreased morphological changes, skeletal muscle damage and inflammation in mdx mice. This indicates that LLLT has potential to decrease progression of Duchenne muscular dystrophy

1H, 15N, and 13C chemical shift assignments of the mosquito odorant binding protein-1 (CquiOBP1) bound to the mosquito oviposition pheromone

An odorant-binding protein from the Southern house mosquito, Culex pipiens quinquefasciatus (Cqui-OBP1) binds to the mosquito oviposition pheromone (MOP), 6-acetoxy-5-hexadecanolide to facilitate the transport of MOP to membrane-bound odorant receptors. We report complete NMR chemical shift assignments of Cqui-OBP1 bound to the MOP pheromone obtained at pH 7.0 and 25°C (BMRB no. 16175)

Delimitación del vocablo Cibernética y otras voces tecnológicas en Periodismo.

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